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Dan Leotta

Senior Engineer






2000-present and while at APL-UW

An upgraded camera-based imaging system for mapping venous blood oxygenation in human skin tissue

Li, J., X. Zhang, L. Qiu, and D.F. Leotta, "An upgraded camera-based imaging system for mapping venous blood oxygenation in human skin tissue," Opt. Commun., 370, 276-282, doi:10.1016/j.optcom.2016.03.030, 2016.

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1 Jul 2016


A camera-based mapping of venous oxygenation saturation SvO2 was further developed.

Monte Carlo method was used for modeling the imaging system.

Curvature and motion correction algorithms were included in the image process.

The spatial resolution for SvO2 map achieved was 1.25 mm×1.25 mm.

The measured SvO2 was validated by a NIRS system and in line with published data.

Development of a duplex ultrasound simulator and preliminary validation of velocity measurements in carotid artery models

Zierler, R.E., D.F. Leotta, K. Sansom, A. Aliseda, M.D. Anderson, and F.H. Sheehan, "Development of a duplex ultrasound simulator and preliminary validation of velocity measurements in carotid artery models," Vasc. Endovascular Surg., 50, 309-316, doi:10.1177/1538574416647502, 2016.

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1 Jul 2016

Duplex ultrasound scanning with B-mode imaging and both color Doppler and Doppler spectral waveforms is relied upon for diagnosis of vascular pathology and selection of patients for further evaluation and treatment. In most duplex ultrasound applications, classification of disease severity is based primarily on alterations in blood flow velocities, particularly the peak systolic velocity (PSV) obtained from Doppler spectral waveforms. We developed a duplex ultrasound simulator for training and assessment of scanning skills.

Custom fenestration templates for endovascular repair of juxtarenal aortic aneurysms

Leotta, D.F., and B.W. Starnes, "Custom fenestration templates for endovascular repair of juxtarenal aortic aneurysms," J. Vasc. Surg., 61, 1637-1641, doi:10.1016/j.jvs.2015.02.016, 2015.

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1 Jun 2015

Physician-modified endovascular grafts, with fenestrations added to accommodate major branch vessels, provide a means for endovascular treatment of abdominal aortic aneurysms that are adjacent to the renal arteries. Manual measurements of vessel origin locations from computed tomography images, however, take time and can lead to errors in the positions of the fenestrations. To make the fenestration process faster and more accurate, we have developed a procedure to create custom templates that serve as patient-specific guides for graft fenestration. We use a three-dimensional printer to create a clear rigid sleeve that replicates the patient's aorta and includes holes placed precisely at the locations of the branch vessels. The sleeve is slipped over the graft, the locations of the openings are marked with a pen, and the fenestrations are created after the sleeve is removed. Custom fenestration templates can potentially save procedural costs and make minimally invasive aortic aneurysm repair available to more patients.

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Fenestration template for endovascular repair of aortic aneurysms

Patent Number: 9,811,613

Dan Leotta, Benjamin Starnes

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7 Nov 2017

To provide simple yet accurate stent graft fenestration, a patient-specific fenestration template is used as a guide for graft fenestration. To generate the fenestration template, a patient's medical imaging data such as CT scan data may be used to generate a 3-D digital model of an aorta lumen of the patient. The aorta lumen may encompass one or more branch vessels, which may be indicated on the 3-D digital model. Based on the 3-D digital model or a segment thereof, the fenestration template may be generated, for example, using 3-D printing technology. The fenestration template may include one or more holes or openings that correspond to the one or more branch vessels. To fenestrate a stent graft, the fenestration template is coupled to the stent graft so that the holes or openings on the fenestration template indicate the fenestration locations.

Supplemental Know How for Pushing, Imaging, and Breaking Kidney Stones

Record of Invention Number: 47878

Mike Bailey, Larry Crum, Bryan Cunitz, Barbrina Dunmire, Vera Khokhlova, Wayne Kreider, John Kucewicz, Dan Leotta


9 Nov 2016

Automated Monitoring of Vascular Flow and Morphology by 3D Ultrasound

Record of Invention Number: 47678

Shahram Aarabi, Dan Leotta, Nathan White


13 Apr 2016

More Inventions

Acoustics Air-Sea Interaction & Remote Sensing Center for Environmental & Information Systems Center for Industrial & Medical Ultrasound Electronic & Photonic Systems Ocean Engineering Ocean Physics Polar Science Center